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Question13.
Depigmentation: when and how?
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问题 13. 何时，如何脱色素?
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•Key points
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•要点
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•If, after consistent treatment(s) for vitiligo, satisfactory repigmentation is not achieved, one can consider depigmentation to avoid the skin
color contrast.
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•如果经过持续的白癜风治疗，没有达到满 意的复色，患者可考虑脱色素来避免肤色 反差。
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Chemicals, such as hydroquinone and monobenzone, have been
used as topical
agents, with increasing doubts as for their
safety profile.
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•化学剂，例如氢醌和莫诺本宗,已被用来作 为此类治疗的外用制剂，但是对其安全性 的质疑越来越多。
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•Many types of lasers (including Q-switched, alexandrite and
Ruby Laser)
have been used successfully alone or in combination with topical chemical depigmentary agents.
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•多种类型的激光（包括 Q
开关、翠绿宝石 和红宝石激光）单用或与外用化学脱色剂 联合应用。
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Cryotherapy has been used with promising results, but
pigment recurrence is always possible.
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•应用冷冻疗法有望有效，但也只是有可能 会出现色素的恢复。
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•Answer
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•解答
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Depigmentation is an option for vitiligo
management that can be used when all repigmentation treatments have failed. The scope
of cutaneous depigmentation is to reach a uniform (white
or very fair) skin color.
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脱色素是当所有复色治疗均失败时应对白 癜风的一种选择，目标是达到肤色的均匀。
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