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题 15 手术治疗白癜风: 何时以及如何治疗?

2019-3-1 13:04| 发布者: admin| 查看: 616| 评论: 0

摘要: 题 15 手术治疗白癜风: 何时以及如何治疗?

Question15. Surgical therapy for vitiligo: when and how?

15 白癜: 何时以及如何治疗?

 

Key points

 

要点


 

Surgical therapy is usually introduced when medical or physical treatments of vitiligo fail.

当药物或物理治疗白癜风无效时,常引入 手术治疗。

It consists of introducing melanocytes from pigmented skin area onto the white patches of the same subject.

 

手术包括从患者有色素的皮肤处取自体黑 素细胞植入白斑处。

  Many different treatments are available including simple skin punch grafting, split thickness grafting, blistering, roof grafting and the most sophisticated melanocyte or keratinocyte-melanocyte suspensions.

 

许多不同的治疗方法可行,包括单纯皮肤 打孔移植,皮片移植术,发疱移植,顶部 嫁接,和最尖端的黑素细胞或角质形成细 -黑素细胞悬浮液技术。

Graft failure, scarring, infection, irregular pigmentation, cobble stoning and the vitiligo kobnerization phenomenon are always possible and limit the use of surgery in vitiligo.

 

移植失败、疤痕、感染、不规则色沉、鹅 卵石样变和白癜风的同形反应都可能发 生,这些限制了手术治疗的应用。

Answer

解答

The surgical option in the treatment of vitiligo is always possible, at least on selected/limited depigmented areas.

 

手术选择 /局限性的色素脱失区域是可行的。

Two main conditions are required:

需具备两个主要条件:

the white vitiligo lesion to be treated should be stable (i.e. avoid surgical procedures in lesions which are progressing no progression of lesions or appearance of additional depigmentation must be evident for at least 2 years).

 

 

白癜皮损 上进行手术——无皮损进展或新增的色素 脱失斑明显变白至少两年)

the white area should be recalcitrant to the main and most effective medical and physiotherapeutic UV-based treatments (lights or lasers).

 

白斑要的效的药物线为基础的物理治疗(光、激光)抵抗。

A number of surgical procedures are possible. Among these are the following:

 

有许多可行的手术方式,主要如下:

punch grafting and mini-grafting

打孔移植和微小移植

epidermal grafting

表皮移植

dermo-epidermal grafting

真表皮移植

suction blisters grafting

负压吸疱移植术

—autologous        melanocyte        suspension transplant

自体黑素细胞悬浮液移植


 

 

treatments with tissue - engineered skin

组织工程皮肤治疗

cultured epidermis with melanocytes

人工培养的含黑素细胞的表皮

 

These are considered to be the most popular procedures.

 

这些是最常用的手术方式

 

Neo-melanogenesis usually begins shortly after


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