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• Polypodium Leucotomos (a fern of the American subtropics) , Ginkgo
Biloba, cucumis melo, alpha lipoic acid, vitamins C and E, polyunsaturated fatty acids, phenylalanine and other
natural substances have been
orally consumed with the purpose of elevating systemic catalase activity in the blood and, thus, decreasing the levels of reactive oxygen species. Recently, curcumin alone, or in combination with capsaicin and resveratrol, has been shown to
affect vitiligo actively.
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•水龙骨（美国亚热带的一种蕨类植物）、银 杏、甜瓜、α-硫辛酸、维生素 C 和 E、多 不饱和脂肪酸、苯丙氨酸及其他天然物质 已被用于口服，旨在提高全身过氧化氢酶 的活性，从而降低活性氧化物的水平。目 前，姜黄素单独使用或结合辣椒素、白藜 芦醇使用已显示可对白癜风产生积极影 响。
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•Answer
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•解答
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There is a clear
inclination of the experts
in the field of vitiligo
research towards considering the appearance and progression of white patches
as being related
to a global
imbalance in the activity of the scavenger mechanism (s), which decreases the levels of reactive oxygen species (ROS), both in blood and in
skin of the vitiligo patients.
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白癜风领域的专家对于这一理论——白斑 的出现和发展与清道夫机制作用过程中的 总体失衡相关——有一个明确的倾向。通过 清道夫机制，可降低白癜风患者皮肤和血液 中的活性氧化物水平。
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Thus, both
local and
systemic use of substances that are able to decrease the levels of reactive oxygen species have been repeatedly proposed.
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因此局部外用和口服降低活性氧化物的物 质一直被反复提倡。
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Most of these substances are mentioned in the Key points
section of this paragraph.
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大多数物质已在本节要点中提及。
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In general, while some studies show remarkably good results
in repigmentation after the use of local or systemic
“natural antioxidants”,
other studies show no benefits.
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总体来说，部分研究表明局部或系统使用 “天然抗氧化剂”对复色有显著效果，但仍 有部分研究表明其无效。
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The Dermatological Scientific Community seems to encourage both oral and local use of the “natural
antioxidants” for treating vitiligo.
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皮肤科学委员会倾向于推荐口服和外用“天 然抗氧化剂”治疗白癜风。
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Nevertheless, defined dosing parameters, double-blind consistent studies on efficacy and safety
profiles of these
natural substances have yet to be clarified.
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然而，这些天然物质确切的剂量参数、关于 其有效性和安全性的资料的双盲一致的研 究还有待进一步阐述。
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